Mathematical fact: 4522 is the number of non-intersecting rook paths joining opposite corners of a 8×3 chessboard.
Trivia: 4522 is an uninteresting number.
Historical date: May 18th is the day in 1268 that the Principality of Antioch, a crusader state, falls to the Mamluk Sultan Baibars in the Battle of Antioch.