General fact: 21280 is a number for which we're missing a fact (submit one to numbersapi at google mail!).
Mathematical fact: 21280 is an unremarkable number.
Trivia: 21280 is a boring number.
Historical date: April 5th is the day in 1609 that Daimyo (Lord) of the Satsuma Domain in southern Kyūshū, Japan, completes his successful invasion of the Ryūkyū Kingdom in Okinawa.